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The Cancer Nanotechnology Plan
Funding activities conducted within the framework of the CNPlan will occur in four areas as detailed below. The first will be to develop three to five CCNEs that will provide engineering and physical science expertise to leverage the cancer biology expertise and access to cancer patients at the Nation’s Comprehensive Cancer Centers, SPOREs, and large population infrastructures, such as the Breast and Colon Cancer Family Registries. Second, the CNPlan will fund cross-disciplinary training programs as a means of fostering the creation of the multidisciplinary teams needed to integrate nanotechnology and cancer biology. Third, the CNPlan will fund focused nanotechnology development initiatives that will be milestone driven and product oriented, with an emphasis on commercialization through small-business and larger private-sector project team members. Fourth, the CNPlan will fund projects that apply nanotechnology in cancer biology and translational research, through basic research project grants and other mechanisms. Since the R01 mechanism has historically not been the best mechanism to fund individual investigator-initiated technology development and application projects, the NCI will also make use of program announcements, requests for applications, and request for proposals, as well as a variety of program management and funding mechanisms that have been shown to be successful in prior technology development programs. The NCI will also examine opportunities through the Small Business Innovation Research/Small Business Technology Transfer Research (SBIR/STTR) programs as well as administrative supplements to existing awards to accelerate the integration of nanotechnology into the NCI research program.
In addition to the largely extramural focus of the CNPlan, a variety of demonstration projects in the NCI intramural program will add to this overall effort by acting as developmental catalysts. For example, the NCI has contracted with a nanotechnology foundry to fabricate materials and provide engineering expertise to aid in vivo projects using nanoscale devices. The NCI’s intramural expertise, when used in this type of synergistic manner, will accelerate the development of new nanotechnology-driven advances in oncology.
Helping guide these programmatic activities will be the Cancer Nanotechnology Working Group (CNWG), which was recently formed from the Cancer Nanotechnology Intramural Working Group and the Cancer Nanotechnology Extramural Intramural Working Group. The CNWG will have a tracking function and will continue (as the two subgroups have for the past year) to act in an advisory capacity as the CNPlan moves forward. The CNWG is playing a key role in planning an NCI-sponsored intramural nanotechnology seminar series scheduled for fall 2004 and coordinating symposia held at regional cancer and advanced technology centers.
The CNPlan will also include development of program evaluation tools related to the programmatic milestones proposed in this plan as well as mechanisms for conducting annual evaluations. The evaluation processes will involve independent, outside review teams and will assess how program activities conducted as part of the CNPlan meet the goals and milestones set forth in this plan. Feedback from these evaluations will facilitate appropriate milestone adjustment course corrections in the implementation of the plan.
(Read More on Free Ebook at PDF Format)
Download The Cancer Nanotechnology Plan.pdf
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